eng Ansari Education and Research Society Journal of Ultra Chemistry 0973-3450 2319-8036 December 2007 3 2 97 102 juc 644 article DILIP B. PATIL 1 PRAKASH R. KAKDE 1 Department of Chemistry, Institute of Science,Nagpur - 440001 (INDIA) <p style="text-align: justify;">The kinetics of the oxidation of oxyhaemoglobin by sodium nitrite has been studied spectrophotometrically. The reaction has been shown to be second order with specific reaction rate of 4.2 x 10¹ M^-1s^-1 at 25.0^oC and&nbsp; at pH 6.80(Phosphate buffer). The energy of activation, frequency factor and entropy of activation are found to be 57.94 kJM^-1, 5.994 x 10¹¹ s^-1 and -27.68 JK^-1mol^-1respectively. In order to probe inside the mechanism, the effect of ionic strength is also investigated. The most likely mechanism is suggested for the reaction.&nbsp;&nbsp;&nbsp;&nbsp;</p> <p>&nbsp;</p> https://journalofchemistry.org/paper/644/ oxyhaemoglobin methaemoglobin oxidation sodium nitrite