Synthesis of Bio-Active Molecule Fluoro-Benzothiazole Comprising Quinazoline Derivatives for Biological and Pharmacological Screening

eng Ansari Education and Research Society Journal of Ultra Chemistry 0973-3450 2319-8036 December 2008 4 2 245 256 juc 736 article Synthesis of Bio-Active Molecule Fluoro-Benzothiazole Comprising Quinazoline Derivatives for Biological and Pharmacological Screening Niladry Sekhar Ghosh, 1 D. Srinivas Rao 1 N. Rama Rao 1 G.M. Sreenivasa 1 E. Jayachandran 1 Raja Reddy 1 P.G. Department of Pharmaceutical Chemistry, S.C.S. College of Pharmacy, Harapanahalli - 583131 (INDIA) <table border="0" cellpadding="4" cellspacing="0" style="width:100%"> <tbody> <tr> <td> <p style="text-align: justify;">Various substituted 2-amino-N-(2'-benzothiazolyl 6'-fluoro-7'-chloro) benzamides and 2-thione-3-(2'-benzothiazolyl 6'-fluoro-7'-chloro)-4-(3H)-quinazolines containing different functional groups have been synthesized by condensing anthranilic acids with substituted 2-aminobenzothiazoles in dry pyridine. The identity of compounds were confirmed on the basis of their spectral (UV, IR, <sup>1</sup>H NMR and MASS) data. Further, they have been screened for their antimicrobial, antiinflammatory and anticonvulsant activities.<br />  </p> </td> </tr> <tr> <td> <p> </p> </td> </tr> </tbody> </table> https://journalofchemistry.org/paper/736/ Fluorine Benzothiazole Quinazoline