eng Ansari Education and Research Society Journal of Ultra Chemistry 0973-3450 2319-8036 December 2008 4 2 265 270 juc 739 article A. Manigaunha 1 M. Uma maheshwari 2 NRI Institute of Diploma Pharmacy, Sajjan Singh Nagar, Raisen Road, Bhopal (INDIA) College of Pharmacy, Sri Ramkrishna Institute of Paramedical Sciences, Coimbatore, Tamilnadu (INDIA) <p style="text-align: justify;"><em>Piper betel</em> plant is one among the great herbals used in folk and tribal medicines in India. It belongs to the family <em>Piperaceae</em> used as ingredients in a chew commonly known as pan. Chemically <em>piper betel</em> containing chavi betel, chavicol, eugenol, cadinene, alkaloids, sugar, tannin, diastase, betel oil, terpene, sesquiterpene. Biologically <em>Piper betel</em> have broad spectrum activities like antifungal, antibacterial, antitumour, hypotensive, respiratory depressant, anthelmintic, cardiotonic and antifertility. We have used liver slice culture model to demonstrate hepatoprotective activity of PBLE <em>in vitro.</em> CCl₄ (20mM) has been used as a hepatotoxin and the cytotoxicity of CCl₄ is estimated by quantitating the release of LDH in the medium. CCl₄ induces twice the amount release of LDH from the liver as compared to the cells from untreated liver tissue and this was significantly reduced in presence of Plant extract (10&micro;g/ml). Our results clearly point out that PBLE mitigates the CCl₄ induced liver damage by decreasing L</p> https://journalofchemistry.org/paper/739/ Assessment of Hepatoprotective Piper Betel Leaves