POLAROGRAPHIC STUDY OF COMPLEXES OF Pb(II) WITH ATENOLOL AT D.M.E.

eng Ansari Education and Research Society Journal of Ultra Chemistry 0973-3450 2319-8036 December 2007 3 1 55 60 puc 788 article POLAROGRAPHIC STUDY OF COMPLEXES OF Pb(II) WITH ATENOLOL AT D.M.E. PRIYANKA DHINGRA (priyankadhingra31@rediffmail.com 1 Shweta Sharma 2 R.S. PANDEY 2 D-168, Jagraj Marg, Bapu Nagar, Jaipur-302004 Rajasthan (INDIA) Assistant Professor, 7, Kailash Vihar, Lal Kothi, Jaipur, 302015, Rajasthan (INDIA) Atenolol [RS),4-{2-hydroxy-3-isopropylaminopropoxy}phenylacetamide] is an antihypertensive drug, used primarily in cardiovascular diseases. The simple complexes of this drug with Pb(II) have been studied by direct current polarography at 25°C and 35°C. The reduction of all complexes is found to be reversible and diffusion controlled involving 2e_ in each case. Deford and Hume's treatment suggests that Atenolol forms 1 : 2 complexes (metal to ligand molar ratio) at 25°C and 35°C. Two very stable complexes PbR+ and PbR2 are identified at two temperatures at µ = 1 (1M KNO3). The values of overall formation constant (log b) obtained are 4.8448, 7.8644 at 25°C and 4.6976, 7.6732 at 35°C. The thermodynamic parameters (DG°, DH°, DS°) have also been reported.   https://journalofchemistry.org/paper/788/ complexes Atenolol