Synthesis of some antimicrobial 3-Aryl-1,2,4- triazolo-8-methyl-thiadiazepin-6-ones

eng Ansari Education and Research Society Journal of Ultra Chemistry 0973-3450 2319-8036 June 2006 2 2 41 44 juc 803 article Synthesis of some antimicrobial 3-Aryl-1,2,4- triazolo-8-methyl-thiadiazepin-6-ones H.K. Singh (hemnt38singh@yahoo.com 1 S. Singh 1 Department of Chemistry, T.D.P.G., College, Jaunpur, (V.B.S.) Purvachal Universtiy, Jaunpur (U.P.) 222002 (INDIA) <p style="text-align: justify;">Cyclodehydration of thiocarbohydrazide with substituted benzoic acid gives, 5-Aryl-4-amino-3-mercapto-1,2,4 triazole.  The requisite 3-Aryl-1,2,4-triazolo-8-methyl-thiadiazepin-6-ones were prepared by refluxing ethyl acetoacetate and 5-Aryl-4-amino-3-mercapto-1,2,4-triazole. The screening results are correlated with the structural features of the tested compounds.        </p> https://journalofchemistry.org/paper/803/ Synthesis of some antimicrobial ones