BIOLOGICALLY ACTIVE QUINAZOLONES: Synthesis of 2-methyl-3(2'-subsituted phenoxymethyl-1', 3', 4'-thiodiazolyl-5 yl) quinazolin-4-ones and their anthelmintic, antibacterial and antiviral activities

eng Ansari Education and Research Society Journal of Ultra Chemistry 0973-3450 2319-8036 June 2006 2 2 127 132 juc 817 article BIOLOGICALLY ACTIVE QUINAZOLONES: Synthesis of 2-methyl-3(2'-subsituted phenoxymethyl-1', 3', 4'-thiodiazolyl-5 yl) quinazolin-4-ones and their anthelmintic, antibacterial and antiviral activities SADHNA PURI 1 SHRADHA SINHA 2 Department of Chemistry, Dayanand Girls College, Kanpur (INDIA) Department of Chemistry, Babu Banarsi Das National Institute of Technology and Management <p style="text-align: justify;">2-Methyl-3-(2-substituted phenoxymetjyl-1, 3, 4-thiodiazolyl-5-yl) quinazolin-4-ones[IV] were synthesized by the reaction of 2-amino-5-subsituted phenoxymethyl-1,3,4-thiadiazole [II] with substituted 2-methyl anthranil [III]. 2-Amino-5 substituted phenoxy methyl-1, 3, 4-thiadiazoles [II] were obtained by the reaction of substituted phenoxy acids [I] with thiosemicarbazide.<br /> Compounds were screened for their anthelmintic, antibacterial and antiviral activities.<br />  </p> https://journalofchemistry.org/paper/817/ Quinazolone Anthelmintic activity Antiviral activity