Synthesis and antimicrobial activity of novel 3-(p-nitro phenoxy methyl)-4-(2,4,6-trinitro- phenyl)-5-aryl-1,2,4-triazole derivatives

eng Ansari Education and Research Society Journal of Ultra Chemistry 0973-3450 2319-8036 June 2006 2 2 179 182 juc 823 article Synthesis and antimicrobial activity of novel 3-(p-nitro phenoxy methyl)-4-(2,4,6-trinitro- phenyl)-5-aryl-1,2,4-triazole derivatives Shobha Singh 1 A.K. Yadav 1 Vandana Singh 1 D.K. Singh 1 Daroga Singh 1 Department of Chemistry, T.D.P.G. College, Jaunpur (U.P.) INDIA <p>The condensation of 3-p-nitrophenoxy methyl acetate and hydrazine hydrate to give p-nitro-phenoxy acetyl hydrazide (1). The hydrazide (1) reacts with various aromatic acid in the presence of POCl3 to give 3-(p-nitro phenoxymethyl)-5-aryl-1,3,4-oxadiazole (3). Further these oxadiazole (3) condensed with 2,4,6-trinitroaniline to yield the title compounds (4). These compounds have been characterized by U.V., I.R. and PMR spectra. The antimicrobial activity of these compounds have also been screened.    </p> https://journalofchemistry.org/paper/823/ antimicrobial activity phenoxy methyl