eng Ansari Education and Research Society Journal of Ultra Chemistry 0973-3450 2319-8036 December 2009 5 3 422 426 juc 877 article A. SREELAKSHMI 1 G SUDHAKARASAI BABU 2 G. DEVALA RAO 2 Department of Biotechnology, Montessori Mahila Kalasala, VIJAYAWADA-520 010 Andhra Pradesh (INDIA) K.V.S. R. Siddhartha College of Pharmaceutical Sciences, VIJAYAWADA-520 010 Andhra Pradesh (INDIA) <p style="text-align: justify;">Ziprasidone is a typical antipsychotic agent. Two simple, sensitive and accurate spectrophotometric methods have been developed for the determination of Ziprasidone hydrochloride (ZPD) in pure state and in its pharmaceutical formulations. The developed Method A is based on the diazocoupling reaction of the Brotton-Marshall&#39;s reagent with drug and it shows maximum absorption at max 540 nm; Linearity in the range of 2-10 pg/mL. Method B is based on the reaction between drug and 1, 10-phenanthroline with ferric chloride and orthophosphoric acid to form a colored chromogen and it shows maximum absorption at A. ,_nax520 nm and Linearity in the range of 4-20 pg/mL. The results obtained were statistically evaluated and were found to be accurate and reproducible.</p> https://journalofchemistry.org/paper/877/ Ziprasidone Spectrophotometric