Study of Complexation of Co (II) ion with Antibiotics Flumquine by Titrimetric Method
Department of Chemistry Dr. C.V. Raman University Kota Bilaspur C.G. India
Deapartment of Chemistry, Govt. PG College -Bilha Bilaspur C.G. India
Email.nbnillisweet@gmail.com
The development and scope of transition metal- coordinated antibiotics have promising pharmacological applications. Metal complexes are very useful to design the slow release and long acting drug. Although most antibiotics do not need metal ions for their biological activities there are a number of antibiotics called metalloantibiotics that require metal ions to function properly, metal ions are therefore known to accelerate drug action. The present study comprises determination of stability constant and thermodynamics of interaction of antibiotics flumequine with transition metal ion Co (II). The formation of 1:1 and 1:2 metal ligand complexes are found to be formed in 50 %( v/v) methanol – water system. The stability constant values for metal-ligand system compared at three temperatures, it is found that value of stability constant decreases with increasing temperature.
Copy the following to cite this article:
NAMITA BHARDWAJ1* and M.K. SINGH2, "Study of Complexation of Co (II) ion with Antibiotics Flumquine by Titrimetric Method", Journal of Ultra Chemistry, Volume 9, Issue 3, Page Number 373-376, 2016Copy the following to cite this URL:
NAMITA BHARDWAJ1* and M.K. SINGH2, "Study of Complexation of Co (II) ion with Antibiotics Flumquine by Titrimetric Method", Journal of Ultra Chemistry, Volume 9, Issue 3, Page Number 373-376, 2016Available from: http://journalofchemistry.org/paper/384/
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