Role of Molecular Redundancy in modeling carbonic anhydrase (CA-II) inhibition
Author:
M.L. GANGWAL1 and SHWETA(THAKUR)RATHORE*2
Affiliation:
1,2P.M.B.Gujarati Science College Indore India
Email:-shweta_rathore02@yahoo.com
Keyword:
Issue Date:
December 2012
Abstract:
The paper deals with the use of Molecular Redundancy for developing QSAR models to predict inhibition values of aromatic & heteroaromatic sulfonamides towards carbonic anhydrase (CA-II isozyme). The regression analysis has shown that out of the pool of topological indices used, the Molecular Redundancy Index (MRI) is the best one for modeling CA inhibitory properties against the CA-II isozyme & that excellent results are obtained using combination of MRI with distance-based topological indices.
Pages:
391-400
ISSN:
2319-8036 (Online) - 0973-3450 (Print)
Source:
DOI:
juc
Copy the following to cite this article:
M.L. GANGWAL1 and SHWETA(THAKUR)RATHORE*2, "Role of Molecular Redundancy in modeling carbonic anhydrase (CA-II) inhibition", Journal of Ultra Chemistry, Volume 8, Issue 3, Page Number 391-400, 2016Copy the following to cite this URL:
M.L. GANGWAL1 and SHWETA(THAKUR)RATHORE*2, "Role of Molecular Redundancy in modeling carbonic anhydrase (CA-II) inhibition", Journal of Ultra Chemistry, Volume 8, Issue 3, Page Number 391-400, 2016Available from: http://journalofchemistry.org/paper/437/
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