Synthesis and Characterization of 5-{2-[(4-substituted phenyl) amino] ethyl}-N-(4-substituted phenyl) 1,3,4-oxadiazole-2-amine as possible fungicides
Department of Chemistry S.C. post College ,Ballia U.P India
3-(4-Bromo anilino) methyl propionate (Ia-f) obtained from 4- bromo aniline and methylacrylate. These compounds further treating with hydrazine hydrate (99%) in ethanol yielded 3-(4-bromo anilino) propionic acid hydrazine (IIa-f), which on further treating with aryl isothiocyanate (0.01 moles) in the presence of ethanol gives the title compounds 5-{2-[(4-substituted phenyl amino) ethyl]-N-(4-substituted phenyl) 1,3,4-oxadiazole-2-amine (IIIa-r). All the synthesize compounds
were well characterized by their elemental and spectral studies. The fungitoxicity of the synthesized compounds were evaluated against Phytophthora infestans and Helminthosporium oryzae.
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*SARIKA SINGH and R.V. PANDEY, "Synthesis and Characterization of 5-{2-[(4-substituted phenyl) amino] ethyl}-N-(4-substituted phenyl) 1,3,4-oxadiazole-2-amine as possible fungicides", Journal of Ultra Chemistry, Volume 8, Issue 3, Page Number 409-414, 2016Copy the following to cite this URL:
*SARIKA SINGH and R.V. PANDEY, "Synthesis and Characterization of 5-{2-[(4-substituted phenyl) amino] ethyl}-N-(4-substituted phenyl) 1,3,4-oxadiazole-2-amine as possible fungicides", Journal of Ultra Chemistry, Volume 8, Issue 3, Page Number 409-414, 2016Available from: http://journalofchemistry.org/paper/439/
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