Department of Chemistry, Shibli  National P.G.College , Azamgarh India

4-Arylthiosemicarbazides (Ia-e) were prepared by mixing appropriate aromatic amines (in NH3) with CS2, sodium chloroacetate followed by hydrazine hydrate. These 4-arylthiosemicarbazides was added in pyridine and thionyl chloride to prepare 5-aryl-4-mercapto-1- sulpho-2,3,5-triazoles (IIa-e). These 5-aryl-4-mercapto-1-sulpho-2,3,5- triazoles were converted to their potassium salts and further treated with appropriate aryl halide to get 5-aryl-4-thioaryl-1-sulpho-2,3,5-
triazoles (IIIa-y). Fungitoxicity of the prepared compounds have been compared with Dithane M-45 a commercial fungicide, for their fungitoxic action against Puccinia recondita and Ustilagonude var. maydis and the screening results have been correlated with the structural features of the prepared compounds.