6-(3'-nitrophenyl)-4-substituted benzylidine-2,3,5-trihydro pyridazin-3-one derivatives are synthesized from 6-(3'-nitrophenyl)-2,3,4,5-tetrahydro pyridazin-3-one by reaction with substiuted aldehydes. Friedal craft acylation of benzene in presence of anhydrous aluminium chloride yield ß-benzoyl propionic acid. After nitration with H₂SO₄ and HNO₃ of the propionic acid yield ß -m-nitrobenzoyl propionic acid, which is cyclised with hydrazine hydrate to form 6-(3'-nitrophenyt)-2,3,4,5-tetrahydro pyridazin-3-one. Ali the

final synthesized compounds are evaluated for anticonvulsant activity by MES (maximal electro shock) method.