Kinetics of oxidation of mixture of glycine and nicotinic acid by chromic acid in presence of hydrochloric acid have been studied. The probable products are ammonia, carbon di oxide, formaldehyde and pyridine- N- oxide. The rate of oxidation decrease with increase in the concentration of hydrochloric acid. Ostwald isolation method is used for study the rate of the reaction. The rate of reaction with respect to [H⁺] is one. Kinetics of oxidation of mixture of glycine and nicotinic acid by chromic acid shows first order reaction. The kinetic parameters such as energy of activation, catalytic constant, temperature coefficient are calculated.