Various substituted 2-amino-N-(2'-benzothiazolyl 6'-fluoro-7'-chloro) benzamides and 2-thione-3-(2'-benzothiazolyl 6'-fluoro-7'-chloro)-4-(3H)-quinazolines containing different functional groups have been synthesized by condensing anthranilic acids with substituted 2-aminobenzothiazoles in dry pyridine. The identity of compounds were confirmed on the basis of their spectral (UV, IR, ¹H NMR and MASS) data. Further, they have been screened for their antimicrobial, antiinflammatory and anticonvulsant activities.