Synthesis and Antimicrobial Activity of Some New Triazino, Triazolo, and Pyrazolopyridazine Derivatives
Author & Affiliation:
F.A. Yassin
Chemistry Department, Faculty of Science Zagazig University, Zagazig (EGYPT)
Keyword:
Synthesis and Antimicrobial Activity, Pyrazolopyridazine Derivatives
Issue Date:
December 2008
Abstract:
Reaction of 3-hydrazino-4,5,6-triphenyl pyridazine 3 with phenacyl bromide afforded triazolopyridazine 4, while, reaction of 3 with different aldehydes gave the corresponding 3-arylidinhydrazinopyridazine derivatives 5a-c which on reaction with Br2/Na2CO3 gave the corresponding triazinopy-ridazines 6a-c. Also, fusion of 3 with ethyl acetoacetate, ethyl benzoylacetate, diethyl malonate and/or ethyl phenyl acetoacetate gave the corresponding pyrazolo and triazinopyridazine derivatives 10, 11, 12 and 13 respectively. The antimicrobial activity of some new compounds has been discussed.
Pages:
271-278
ISSN:
2319-8036 (Online) - 0973-3450 (Print)
Source:
PDF:
DOI:
juc
Copy the following to cite this article:
F. Yassin, "Synthesis and Antimicrobial Activity of Some New Triazino, Triazolo, and Pyrazolopyridazine Derivatives ", Journal of Ultra Chemistry, Volume 4, Issue 2, Page Number 271-278, 2018Copy the following to cite this URL:
F. Yassin, "Synthesis and Antimicrobial Activity of Some New Triazino, Triazolo, and Pyrazolopyridazine Derivatives ", Journal of Ultra Chemistry, Volume 4, Issue 2, Page Number 271-278, 2018Available from: http://journalofchemistry.org/paper/740/
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License
