Acid hydrazide when condensed with carbon disulphide in ethanolic potassium hydroxide yielded potassium dithiocarbazinate(2). On heating (2) and acid hydrazides yielded compounds (3a-I). the compounds (3a-I) were reacted with chloroacetic acid and yielded compounds (4a-I). the antimicrobial activities of the synthesized compounds have also been evaluated. The structures of the same compounds were established on the basis of analytical and spectral data.