MIXED LIGAND COMPLEX FORMATION OF M2+ IONS WITH OMEPRAZOLE AND b- ALANINE
Peptic ulcer is mainly caused by stress and dietary factors. Gastric acid is responsible for peptic ulcer. Proton pump inhibitors (PPI) play important role to suppress the stomach acids. Omeprazole is one of the important PPI drug. The interaction of Cd (11), Co (11), Cu (11), Mn (11) and Zn (11) ions with Omeprazole, in presence of a amino-acid, b-Alanine, has been investigated potentiometrically at 26°C and 36°C and at 0.1M (NaNO3) ionic strength. The stability constants of the Binary (1:1) and ternary (l:l:l) complexes indicate the stability order as : Co (11)< Cu (11) < Mn (11) < Zn (11) < Cd (11). D log K values obtained are positive and suggest greater stabilisation of ternary complexes. The calculated values of thermodynamic parameters (D G, D H and D S) indicate that the interactions are enthalpy characterised.
Copy the following to cite this article:
S. Shrivastava; A. C. R. Tiwari, "MIXED LIGAND COMPLEX FORMATION OF M2+ IONS WITH OMEPRAZOLE AND b- ALANINE", Journal of Ultra Chemistry, Volume 2, Issue 2, Page Number 104-106, 2018Copy the following to cite this URL:
S. Shrivastava; A. C. R. Tiwari, "MIXED LIGAND COMPLEX FORMATION OF M2+ IONS WITH OMEPRAZOLE AND b- ALANINE", Journal of Ultra Chemistry, Volume 2, Issue 2, Page Number 104-106, 2018Available from: http://journalofchemistry.org/paper/813/
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