BIOLOGICALLY ACTIVE QUINAZOLONES: Synthesis of 2-methyl-3(2'-subsituted phenoxymethyl-1', 3', 4'-thiodiazolyl-5 yl) quinazolin-4-ones and their anthelmintic, antibacterial and antiviral activities
Author & Affiliation:
SADHNA PURI
Department of Chemistry, Dayanand Girls College, Kanpur (INDIA)
SHRADHA SINHA
Department of Chemistry, Babu Banarsi Das National Institute of Technology and Management
Keyword:
Quinazolone, Anthelmintic activity, Antiviral activity
Issue Date:
June 2006
Abstract:
2-Methyl-3-(2-substituted phenoxymetjyl-1, 3, 4-thiodiazolyl-5-yl) quinazolin-4-ones[IV] were synthesized by the reaction of 2-amino-5-subsituted phenoxymethyl-1,3,4-thiadiazole [II] with substituted 2-methyl anthranil [III]. 2-Amino-5 substituted phenoxy methyl-1, 3, 4-thiadiazoles [II] were obtained by the reaction of substituted phenoxy acids [I] with thiosemicarbazide.
Compounds were screened for their anthelmintic, antibacterial and antiviral activities.
Pages:
127-132
ISSN:
2319-8036 (Online) - 0973-3450 (Print)
Source:
PDF:
DOI:
juc
Copy the following to cite this article:
S. Puri; S. Sinha, "BIOLOGICALLY ACTIVE QUINAZOLONES: Synthesis of 2-methyl-3(2'-subsituted phenoxymethyl-1', 3', 4'-thiodiazolyl-5 yl) quinazolin-4-ones and their anthelmintic, antibacterial and antiviral activities", Journal of Ultra Chemistry, Volume 2, Issue 2, Page Number 127-132, 2018Copy the following to cite this URL:
S. Puri; S. Sinha, "BIOLOGICALLY ACTIVE QUINAZOLONES: Synthesis of 2-methyl-3(2'-subsituted phenoxymethyl-1', 3', 4'-thiodiazolyl-5 yl) quinazolin-4-ones and their anthelmintic, antibacterial and antiviral activities", Journal of Ultra Chemistry, Volume 2, Issue 2, Page Number 127-132, 2018Available from: http://journalofchemistry.org/paper/817/
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