The condensation of 3-p-nitrophenoxy methyl acetate and hydrazine hydrate to give p-nitro-phenoxy acetyl hydrazide (1). The hydrazide (1) reacts with various aromatic acid in the presence of POCl3 to give 3-(p-nitro phenoxymethyl)-5-aryl-1,3,4-oxadiazole (3). Further these oxadiazole (3) condensed with 2,4,6-trinitroaniline to yield the title compounds (4). These compounds have been characterized by U.V., I.R. and PMR spectra. The antimicrobial activity of these compounds have also been screened.
Copy the following to cite this article:
S. Singh; A. Yadav; V. Singh; D. Singh; D. Singh, "Synthesis and antimicrobial activity of novel 3-(p-nitro phenoxy methyl)-4-(2,4,6-trinitro- phenyl)-5-aryl-1,2,4-triazole derivatives", Journal of Ultra Chemistry, Volume 2, Issue 2, Page Number 179-182, 2018Copy the following to cite this URL:
S. Singh; A. Yadav; V. Singh; D. Singh; D. Singh, "Synthesis and antimicrobial activity of novel 3-(p-nitro phenoxy methyl)-4-(2,4,6-trinitro- phenyl)-5-aryl-1,2,4-triazole derivatives", Journal of Ultra Chemistry, Volume 2, Issue 2, Page Number 179-182, 2018Available from: http://journalofchemistry.org/paper/823/