Journal of Chemistry

Novel spectrophotometric methods for the determination of lornoxicam in pharmaceutical dosage forms

Author & Affiliation:
E. Venumadhav
Chief Opeating Officer, Veeda CR, Ahmedabad, Gujrat, State (INDIA)
T. Neha
K.V.S.R. Siddartha College of Pharmaceutical Science, Vijaywada- 520010 A.P. (INDIA)
P. Bhargavi
K.V.S.R. Siddartha College of Pharmaceutical Science, Vijaywada- 520010 A.P. (INDIA)
Amreen Nishat
K.V.S.R. Siddartha College of Pharmaceutical Science, Vijaywada- 520010 A.P. (INDIA)
A. Swetha
K.V.S.R. Siddartha College of Pharmaceutical Science, Vijaywada- 520010 A.P. (INDIA)
G. Devala Rao
K.V.S.R. Siddartha College of Pharmaceutical Science, Vijaywada- 520010 A.P. (INDIA)
Keyword:
Spectrophotometry, Lornoxicam, Pharmaceutical formulations
Issue Date:
December 2010
Abstract:


Three simple and sensitive visible spectrophotometric methods (A, B & C) for the determination of Lornoxicam (LOC) in bulk and pharmaceutical dosage forms are described. They are based on the formation of colored species by Redox reaction with Folin-Ciocalteau (FC) phenol's reagent under alkaline conditions (method A; ëmax 700 nm) or oxidation followed by complex formation with 1,10- Phenanthroline (PTL) in presence of Ferric Chloride (method B; ëmax 510 nm) or oxidative coupling of the drug with 3-methyl- 2-Benzothiazolinone Hydrazone HCl (MBTH) in the presence of Sodium meta periodate (method C; ëmax 620 nm). These methods were extended to the analysis of pharmaceutical formulations and results compared with the reference method.
 

Pages:
365-369
ISSN:
2319-8036 (Online) - 0973-3450 (Print)
Source:
DOI:
juc

Copy the following to cite this article:

E. Venumadhav; T. Neha; P. Bhargavi; A. Nishat; A. Swetha; G. D. Rao, " Novel spectrophotometric methods for the determination of lornoxicam in pharmaceutical dosage forms", Journal of Ultra Chemistry, Volume 6, Issue 3, Page Number 365-369, 2018

Copy the following to cite this URL:

E. Venumadhav; T. Neha; P. Bhargavi; A. Nishat; A. Swetha; G. D. Rao, " Novel spectrophotometric methods for the determination of lornoxicam in pharmaceutical dosage forms", Journal of Ultra Chemistry, Volume 6, Issue 3, Page Number 365-369, 2018

Available from: http://journalofchemistry.org/paper/599/

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