Three simple and sensitive visible spectrophotometric methods (A, B & C) for the determination of Lornoxicam (LOC) in bulk and pharmaceutical dosage forms are described. They are based on the formation of colored species by Redox reaction with Folin-Ciocalteau (FC) phenol's reagent under alkaline conditions (method A; ëmax 700 nm) or oxidation followed by complex formation with 1,10- Phenanthroline (PTL) in presence of Ferric Chloride (method B; ëmax 510 nm) or oxidative coupling of the drug with 3-methyl- 2-Benzothiazolinone Hydrazone HCl (MBTH) in the presence of Sodium meta periodate (method C; ëmax 620 nm). These methods were extended to the analysis of pharmaceutical formulations and results compared with the reference method.
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E. Venumadhav; T. Neha; P. Bhargavi; A. Nishat; A. Swetha; G. D. Rao, " Novel spectrophotometric methods for the determination of lornoxicam in pharmaceutical dosage forms", Journal of Ultra Chemistry, Volume 6, Issue 3, Page Number 365-369, 2018Copy the following to cite this URL:
E. Venumadhav; T. Neha; P. Bhargavi; A. Nishat; A. Swetha; G. D. Rao, " Novel spectrophotometric methods for the determination of lornoxicam in pharmaceutical dosage forms", Journal of Ultra Chemistry, Volume 6, Issue 3, Page Number 365-369, 2018Available from: http://journalofchemistry.org/paper/599/